Amyloid and Related Disorders: Surgical Pathology and by Maria M. Picken MD PhD FASN, Ahmet Dogan, Guillermo A.

By Maria M. Picken MD PhD FASN, Ahmet Dogan, Guillermo A. Herrera

The moment variation of this article offers an outline of the newest advancements during this sector together with scientific presentation, etiology, pathogenesis, and differential prognosis. the reason for numerous treatments, together with transplantation, is mentioned and tissue prognosis (its pitfalls and methods for warding off them) and laboratory aid are incorporated. The involvement of all significant organ platforms together with renal/genitourinary, cardiac, gastrointestinal, pulmonary, peripheral nerve/central anxious process, tender tissue, pores and skin, lymph node/spleen and bone marrow pathology is additionally covered.

Amyloid and comparable issues, moment Edition can be necessary to really expert and normal pathologists in addition to cytopathologists. different doctors can also take advantage of this concise replace at the systemic amyloidoses.

Show description

Read Online or Download Amyloid and Related Disorders: Surgical Pathology and Clinical Correlations PDF

Similar pathology books

Atlas of Ear, Nose and Throat Pathology

Many pathologists have little acquaintance with ear, nostril concomitant biopsy became typical within the and throat pathology. a few obtain few specimens from administration of throat problems. it's was hoping that. through ENT tissues; others are deterred from deeper learn of the book of this Atlas, pathologists receiving basically fabric that emanates from areas the traditional anatomy occasional specimens could be guided of their provision of of that's so forbidding in its complexity and holds no a document precious to the clinician and those that are concerned familiarity via post-mortem research, for, except with a bigger ENT carrier could be providec with a advisor the larynx, there's frequently no compelling indication for to the deeper realizing of the topic.

Extra resources for Amyloid and Related Disorders: Surgical Pathology and Clinical Correlations

Sample text

M. Nuvolone et al. 65. Simons JP, et al. Pathogenetic mechanisms of amyloid A amyloidosis. Proc Natl Acad Sci USA. 2013;110:16115–20. 66. Harris DL, King E, Ramsland PA, Edmundson AB. Binding of nascent collagen by amyloidogenic light chains and amyloid fibrillogenesis in monolayers of human fibrocytes. J Mol Recognit. 2000;13:198–212. 67. Stevens FJ, Kisilevsky R. Immunoglobulin light chains, glycosaminoglycans, and amyloid. Cell Mol Life Sci. 2000;57:441–9. 68. Yan SD, et al. Receptor-dependent cell stress and amyloid accumulation in systemic amyloidosis.

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins. Proc Natl Acad Sci USA. 1998;95:6448–53. 72. Hartley DM, et al. Protofibrillar intermediates of amyloid beta-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons. J Neurosci. 1999;19:8876–84. 73. Walsh DM, et al. Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal longterm potentiation in vivo. Nature. 2002;416:535–9. 74.

67. Stevens FJ, Kisilevsky R. Immunoglobulin light chains, glycosaminoglycans, and amyloid. Cell Mol Life Sci. 2000;57:441–9. 68. Yan SD, et al. Receptor-dependent cell stress and amyloid accumulation in systemic amyloidosis. Nat Med. 2000;6:643–51. 69. Sousa MM, Cardoso I, Fernandes R, Guimaraes A, Saraiva MJ. Deposition of transthyretin in early stages of familial amyloidotic polyneuropathy: evidence for toxicity of nonfibrillar aggregates. Am J Pathol. 2001;159:1993–2000. 70. Andersson K, Olofsson A, Nielsen EH, Svehag SE, Lundgren E.

Download PDF sample

Rated 4.62 of 5 – based on 43 votes